Automated PET tracer classification in multi-site, multi-cohort studies using deep learning
Deep learning classifies brain PET radiotracers directly from scans across sites and cohorts, improving metadata quality control.
Deep learning classifies brain PET radiotracers directly from scans across sites and cohorts, improving metadata quality control.
A study of diffusion MRI signatures linked to hypertensive arteriopathy and cerebral amyloid angiopathy in cerebral small vessel disease.
We developed a machine learning framework to quantify disease heterogeneity and progression in multiple system atrophy and Parkinson's disease using structural and diffusion MRI.
A book chapter reviewing AI applications in dementia research including imaging biomarkers, machine learning classification, and disease progression modeling.
We applied the THETA score to investigate cognitive resilience mechanisms in individuals with heterogeneous global tau burden.
We evaluated ComBat and Deming regression for harmonizing white matter hyperintensity measurements across scanners and demonstrated that harmonization challenges persist.
We used diffusion imaging measures to distinguish between hypertensive arteriopathy and cerebral amyloid angiopathy contributions to small vessel disease.
We developed brain age prediction models designed to be invariant to MRI scanner changes for use in aging and dementia studies.
We developed an automatic classification system for head MR series to streamline neuroimaging data management.
MRI, plasma biomarkers, genetics, cardiovascular risk, and lifestyle measures were compared for predicting cognitive decline.
THETA is a machine-learning tau PET measure that captures the spatial pattern of tau deposition across the brain in Alzheimer's disease.
We applied AI methods to neuroimaging data to detect hypersomnia and characterize its neurobiological correlates.
We developed machine learning models integrating polygenic risk scores for enhanced prediction of Alzheimer's disease imaging and fluid biomarker endophenotypes.
We validated the THETA score using longitudinal PET data and histopathology, demonstrating its association with disease progression and neuropathological staging.
We developed a machine learning method to identify transition points in Alzheimer's disease biomarkers as a supplement to the reliable worsening method.
We used brain age models to quantify the impact of chronic medical conditions on dementia risk.
We compared NODDI diffusion imaging with structural MRI for sensitivity to neurodegenerative changes.
We demonstrated that genetic risk scores enhance the diagnostic accuracy of plasma biomarkers for detecting brain amyloidosis.
We developed a novel method to encode two-way epistatic interactions between single nucleotide polymorphisms for machine learning applications in genetics.
A systematic comparison questions the reliability of widely used cross-scanner harmonization methods for structural MRI.
We developed the first deep learning application for detecting hip osteoarthritis from 2-D summation images derived from routine clinical CT scans.
We developed a filter using alkali-activated blast furnace slag for dye removal from wastewater.
We identified CT-based bone structural characteristics that discriminate patients with low-energy acetabular fractures from matched controls.
We identified structural risk factors for low-energy acetabular fractures in the elderly using computed tomography.