We applied the THETA score to investigate cognitive resilience mechanisms in individuals with heterogeneous global tau burden.
We used diffusion imaging measures to distinguish between hypertensive arteriopathy and cerebral amyloid angiopathy contributions to small vessel disease.
We used brain age models to quantify the impact of chronic medical conditions on dementia risk.
We examined vascular risk factors, gait measures, behavioral symptoms, and plasma biomarkers as indicators of vascular contributions to cognitive impairment and dementia.
We evaluated non-imaging measures for predicting variability in white matter changes relevant to vascular contributions to cognitive impairment and dementia.